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Unveiling the mechanisms of nephrotoxicity caused by nephrotoxic compounds using toxicological network analysis

10 Nov 2023

Abstract excerpt

Billions of people worldwide have experienced irreversible kidney injuries, which is mainly attributed to the complexity of drug-induced nephrotoxicity. Consequently, there is an urgent need for uncovering the mechanisms of nephrotoxicity caused by compounds. In the present study, a network-based methodology was applied to explore the mechanisms of nephrotoxicity induced by specific compounds. Initially, a total...

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PMID: 38074898
DOI: 10.1016/j.omtn.2023.102075

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