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Article

Effectiveness of gene-expression connectivity analysis for evaluating treatment effects of frequent medicines on kidney in IgA nephropathy

2022-11-07

Abstract excerpt

<h4>Introduction: </h4> IgA nephropathy (IgAN) is a leading cause of end-stage kidney disease worldwide. It is still challenging to assess the treatment effects of frequently used IgAN drugs. <h4>Methods: </h4> We collected gene-expression profiles of renal tissues from eligible IgAN studies in Gene Expression Omnibus (GEO) dataset. The IgAN drugs were identified by InChIKey from Connectivity Map (CMap) L1000 to c...

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Literature Corpus work
ee6b650a-a68d-5f8e-83d0-c87331b37346
DOI
10.21203/rs.3.rs-2226299/v1
Open publication

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Effectiveness of gene-expression connectivity analysis for evaluating treatment effects of frequent medicines on kidney in IgA nephropathyDOI 10.21203/rs.3.rs-2226299/v1
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