Article

Utilizing gene co-expression networks with the rat kidney TXG-MAPr tool to enhance safety assessment, biomarker identification and human translation

2023-11-05

Abstract excerpt

<h4>Summary</h4> Toxicogenomic data represent a valuable source of biological information at molecular and cellular level to understand unanticipated organ toxicities. Weighted gene co-expression networks analysis can reduce the complexity of gene-level transcriptomic data to a set of biological response-networks useful for providing insights into mechanisms of drug-induced adverse outcomes. In this study, we hav...

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Literature Corpus work: ad9c0e84-8f09-5a19-9855-91ba1e9c1043
DOI: 10.1101/2023.11.03.565444

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