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Article

BRCA-associated ovarian cancer: from molecular genetics to risk management.

BioMed research international - 1 Jan 2014

Girolimetti Giulia, Perrone Anna Myriam, Santini Donatella, Barbieri Elena, Guerra Flora, Ferrari Simona, Zamagni Claudio, De Iaco Pierandrea, Gasparre Giuseppe, Turchetti Daniela

Abstract excerpt

Ovarian cancer (OC) mostly arises sporadically, but a fraction of cases are associated with mutations in BRCA1 and BRCA2 genes. The presence of a BRCA mutation in OC patients has been suggested as a prognostic and predictive factor. In addition, the identification of asymptomatic carriers of such mutations offers an unprecedented opportunity for OC prevention. This review is aimed at exploring the current...

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Source

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Identifiers

PMID: 25136623
DOI: 10.1155/2014/787143
PMCID: PMC4129974

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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