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Article

Oligonucleotide-Based Therapeutics for STAT3 Targeting in Cancer—Drug Carriers Matter

29 Nov 2023

Abstract excerpt

High expression and phosphorylation of signal transducer and transcription activator 3 (STAT3) are correlated with progression and poor prognosis in various types of cancer. The constitutive activation of STAT3 in cancer affects processes such as cell proliferation, apoptosis, metastasis, angiogenesis, and drug resistance. The importance of STAT3 in cancer makes it a potential therapeutic target. Various methods...

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PMID: 38067351
DOI: 10.3390/cancers15235647

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