Article
PredictONCO: a web tool supporting decision-making in precision oncology by extending the bioinformatics predictions with advanced computing and machine learning.
Briefings in bioinformatics - 22 Nov 2023
Stourac Jan, Borko Simeon, Khan Rayyan T, Pokorna Petra, Dobias Adam, Planas-Iglesias Joan, Mazurenko Stanislav, Pinto Gaspar, Szotkowska Veronika, Sterba Jaroslav, Slaby Ondrej, Damborsky Jiri, Bednar David
Abstract excerpt
PredictONCO 1.0 is a unique web server that analyzes effects of mutations on proteins frequently altered in various cancer types. The server can assess the impact of mutations on the protein sequential and structural properties and apply a virtual screening to identify potential inhibitors that could be used as a highly individualized therapeutic approach, possibly based on the drug repurposing. PredictONCO...
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