Article

OpenOncology: An Open-Source Framework for Evidence-Based Drug Matching and De Novo Custom Drug Discovery in Precision Oncology

2026-05-18

Abstract excerpt

<title>Abstract</title> <p>Background Precision oncology depends on rapid, evidence-based matching of tumor variants to approved therapies. However, two compounding problems limit access for most patients worldwide: first, the interpretation infrastructure remains locked behind institutional subscriptions; second, even well-resourced precision oncology pipelines return empty outputs when no approved or repurpose...

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Literature Corpus work: dcd67f55-39d2-5881-885e-7a393598829d
DOI: 10.21203/rs.3.rs-9707913/v1

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