Article

Precise interpretation and prioritization of sequence variants with Onkopus for supporting molecular tumor boards

2024-09-25

Abstract excerpt

One of the major challenges in precision medicine is the identification of pathogenic, actionable variants and the selection of personalized treatments. We present Onkopus, a variant interpretation framework, based on a modular architecture, for interpreting and prioritizing genetic alterations in cancer patients. We show that aggregation and harmonization of clinical databases, coupled with querying of these data...

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Identifiers and source

Literature Corpus work: 53355144-b909-51fe-813c-ec254153710b
DOI: 10.1101/2024.09.24.24314298

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