Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Longitudinal assessment of skeletal muscle functional mechanics in the DE50-MD dog model of Duchenne muscular dystrophy.

Disease models & mechanisms - 1 Dec 2023

Riddell Dominique O, Hildyard John C W, Harron Rachel C M, Taylor-Brown Frances, Kornegay Joe N, Wells Dominic J, Piercy Richard J

Abstract excerpt

Duchenne muscular dystrophy (DMD), caused by mutations in the dystrophin (DMD) gene, is associated with fatal muscle degeneration and atrophy. Patients with DMD have progressive reductions in skeletal muscle strength and resistance to eccentric muscle stretch. Using the DE50-MD dog model of DMD, we assessed tibiotarsal joint (TTJ) flexor and extensor force dynamics, and the resistance of dystrophic muscle to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dogs
Share to Dystrophin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infant

Share to Muscle Contraction

Share to Muscle, Skeletal

Share to Muscle Strength

Share to Muscular Dystrophy, Duchenne

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 38050706
DOI: 10.1242/dmm.050395
PMCID: PMC10753191

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Longitudinal assessment of skeletal muscle functional mechanics in the DE50-MD dog model of Duchenne muscular dystrophy.PMID 38050706Read ↗

The skeletal muscle phenotype of the DE50-MD dog model of Duchenne muscular dystrophySemantic proximity Read ↗

Longitudinal assessment of blood-borne musculoskeletal disease biomarkers in the DE50-MD dog model of Duchenne muscular dystrophySemantic proximity Read ↗

Longitudinal trajectories of muscle impairments in growing boys with Duchenne muscular dystrophySemantic proximity Read ↗

Eccentric contraction injury in dystrophic canine muscle.Semantic proximity Read ↗

Evaluation of a six-minute walk test in the DE50-MD canine model of Duchenne muscular dystrophy and its effect on blood-borne biomarkersSemantic proximity Read ↗

Long-term, age-associated activity quantification in the DE50-MD dog model of Duchenne muscular dystrophy (DMD)Semantic proximity Read ↗

Dystrophin-negative slow-twitch soleus muscles are not susceptible to eccentric contraction induced injury over the lifespan of the mdx mouse.Semantic proximity Read ↗

Physical therapy assessment tools to evaluate disease progression and phenotype variability in Golden Retriever muscular dystrophy.Semantic proximity Read ↗

Quantitative phenotyping of Duchenne muscular dystrophy dogs by comprehensive gait analysis and overnight activity monitoring.Semantic proximity Read ↗

The preclinical cardiac phenotype of the DE50-MD dog model of Duchenne muscular dystrophySemantic proximity Read ↗

Lifespan analysis of dystrophic <i>mdx</i> fast-twitch muscle morphology and its impact on contractile functionSemantic proximity Read ↗

Characterization of Gait Kinematics and Muscle Function in Becker Muscular Dystrophy Pigs: a pilot studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.