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Monitoring of First-line Drug Resistance Mutations Outside the Scope of Xpert MTB/RIF Ultra is Needed for Successful Control of DR-TB in Southern Mozambique.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 10 Apr 2024

Mariner-Llicer Carla, Saavedra Cervera Belén, Mambuque Edson, Gomes Neide, Munguambe Shilzia, Villamayor Luis, Cancino-Muñoz Irving, Torres-Puente Manuela, Nguenha Dinis, Respeito Durval, Tembe Gustavo, López Mariana G, Comas Iñaki, García-Basteiro Alberto L

Abstract excerpt

Multidrug-resistant(MDR) tuberculosis in Southern Africa is of great concern, exacerbated by the spread of a clone harboring a mutation missed by Xpert Ultra. In Southern Mozambique, the presence of such mutation and rising cases of non-MDR isoniazid resistance highlights the need to ensure accurate detection of antimicrobial-resistance in the country.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38048599
DOI: 10.1093/cid/ciad684
PMCID: PMC11006097

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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