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Rifampicin-Monoresistant Tuberculosis Is Not the Same as Multidrug-Resistant Tuberculosis: a Descriptive Study from Khayelitsha, South Africa.

Antimicrobial agents and chemotherapy - 18 Oct 2021

Salaam-Dreyer Zubeida, Streicher Elizabeth M, Sirgel Frederick A, Menardo Fabrizio, Borrell Sonia, Reinhard Miriam, Doetsch Anna, Cudahy Patrick G T, Mohr-Holland Erika, Daniels Johnny, Dippenaar Anzaan, Nicol Mark P, Gagneux Sebastien, Warren Robin M, Cox Helen

Abstract excerpt

Rifampin monoresistance (RMR; rifampin resistance and isoniazid susceptibility) accounts for 38% of all rifampin-resistant tuberculosis (RR-TB) in South Africa and is increasing. We aimed to compare RMR-TB with multidrug-resistant TB (MDR-TB) in a setting with high TB, RR-TB, and HIV burdens. Patient-level clinical data and stored RR Mycobacterium tuberculosis isolates from 2008 to 2017 with available...

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Identifiers

PMID: 34460307
DOI: 10.1128/AAC.00364-21
PMCID: PMC8522772

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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