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Transcriptomics and proteomics revealed sex differences in human pulmonary microvascular endothelial cells

4 Dec 2023

Abstract excerpt

There is marked sexual dimorphism in the development and progression of pulmonary hypertension. We show differences in RNA and protein expression between female and male human pulmonary microvascular endothelial cells grown under conditions of physiological shear stress, which identify sex-different cellular pathways both in normoxia and hypoxia. Importantly, these differences were detected in the absence of sex...

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PMID: 38047313
DOI: 10.1152/physiolgenomics.00051.2023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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