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Article

Transcriptomics analysis of allergen-induced inflammatory gene expression in the Four-Core Genotype mouse model.

Physiological genomics - 1 Feb 2024

Ekpruke Carolyn Damilola, Alford Rachel, Rousselle Dustin, Babayev Maksat, Sharma Shikha, Commodore Sarah, Buechlein Aaron, Rusch Douglas B, Silveyra Patricia

Abstract excerpt

Sex differences in allergic inflammation have been reported, but the mechanisms underlying these differences remain unknown. Contributions of both sex hormones and sex-related genes to these mechanisms have been previously suggested in clinical and animal studies. Here, Four-Core Genotypes (FCG) mouse model was used to study the inflammatory response to house dust mite (HDM) challenge and identify differentially...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38047309
DOI: 10.1152/physiolgenomics.00112.2023
PMCID: PMC11281817

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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