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Article

Gonadal sex and chromosome complement influence the gut microbiome in a mouse model of allergic airway inflammation.

Physiological genomics - 1 Jun 2024

Ekpruke Carolyn Damilola, Alford Rachel, Parker Erik, Silveyra Patricia

Abstract excerpt

Evidence abounds that gut microbiome components are associated with sex disparities in the immune system. However, it remains unclear whether the observed sex disparity in asthma incidence is associated with sex-dependent differences in immune-modulating gut microbiota, and/or its influence on allergic airway inflammatory processes. Using a mouse model of house dust mite (HDM)-induced allergic inflammation and...

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Identifiers

PMID: 38640403
DOI: 10.1152/physiolgenomics.00003.2024
PMCID: PMC11368565

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