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Article

Single-cell transcriptomic analysis of corneal organoids during development

30 Nov 2023

Abstract excerpt

Corneal organoids are useful tools for disease modeling and tissue transplantation; however, they have not yet been well studied during maturation. We characterized human iPSC-derived corneal organoids at 1, 2, 3, and 4 months of development using single-cell RNA sequencing to determine the cellular heterogeneity at each stage. We found pluripotent cell clusters committed to epithelial cell lineage at 1 month;...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38039970
DOI: 10.1016/j.stemcr.2023.10.022

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