Article

Deciphering the heterogeneity of differentiating hPSC-derived corneal limbal stem cells through single-cell RNA-sequencing

2023-11-24

Abstract excerpt

<h4>Summary</h4> A comprehensive understanding of the human pluripotent stem cell (hPSC) differentiation process stands as a prerequisite for the development hPSC-based therapeutics. In this study, single-cell RNA-sequencing (scRNA-seq) was performed to decipher the heterogeneity during differentiation of three hPSC lines towards corneal limbal stem cells (LSCs). The scRNA-seq data revealed nine clusters encompas...

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Literature Corpus work: 5893801a-2e27-536e-ad64-bfec9f3b660d
DOI: 10.1101/2023.11.24.568553

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