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A single-cell RNA-seq analysis unravels the heterogeneity of primary cultured human corneal endothelial cells

8 Jun 2023

Abstract excerpt

The cornea is a transparent and avascular tissue located in front of the eye. Its inner surface is lined by a monolayer of corneal endothelial cells (CECs), which maintain the cornea transparency. CECs remain arrested in a non-proliferative state and damage to these cells can compromise their function leading to corneal opacity. The primary culture of donor-derived CECs is a promising cell therapy. It confers the...

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PMID: 37291161
DOI: 10.1038/s41598-023-36567-6

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