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Single cell RNA-seq of human cornea organoids identifies cell fates of a developing immature cornea

28 Oct 2022

Abstract excerpt

The cornea is a protective and refractive barrier in the eye crucial for vision. Understanding the human cornea in health, disease, and cell-based treatments can be greatly advanced with cornea organoids developed in culture from induced pluripotent stem cells. While a limited number of studies have investigated the single-cell transcriptomic composition of the human cornea, its organoids have not been examined...

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PMID: 36712326
DOI: 10.1093/pnasnexus/pgac246

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