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Article

Molecular characteristics and spatial distribution of adult human corneal cell subtypes

11 Aug 2021

Abstract excerpt

Bulk RNA sequencing of a tissue captures the gene expression profile from all cell types combined. Single-cell RNA sequencing identifies discrete cell-signatures based on transcriptomic identities. Six adult human corneas were processed for single-cell RNAseq and 16 cell clusters were bioinformatically identified. Based on their transcriptomic signatures and RNAscope results using representative cluster marker...

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PMID: 34381080
DOI: 10.1038/s41598-021-94933-8

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