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Article

Epigenetic age biomarkers and risk assessment in adult spinal deformity: a novel association of biological age with frailty and disability

1 Dec 2023

Abstract excerpt

OBJECTIVE: Surgery for spinal deformity has the potential to improve pain, disability, function, self-image, and mental health. These surgical procedures carry significant risk and require careful selection, optimization, and risk assessment. Epigenetic clocks are age estimation tools derived by measuring the methylation patterns of specific DNA regions. The study of biological age in the adult deformity...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38039536
DOI: 10.3171/2023.10.spine23435

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