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Epigenetic age acceleration in idiopathic pulmonary fibrosis revealed by DNA methylation clocks

19 Feb 2025

Abstract excerpt

Using epigenetic clocks, we found a notable acceleration of biological aging in IPF tissues, particularly in DunedinPACE, suggesting that the biological aging process in IPF is accelerated and closely related to the severity of the disease. The study also underscores DNA methylation's potential as a biomarker for IPF, as well as the dynamics of epigenetic aging and the need to consider biological age in medical...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39970931
DOI: 10.1152/ajplung.00171.2024

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