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MskAge - An Epigenetic Biomarker of Musculoskeletal Age Derived from a Genetic Algorithm Islands Model

2023-05-05

Abstract excerpt

<h4>Background</h4> Age is a significant risk factor for functional decline and disease of the musculoskeletal system, yet few biomarkers exist to facilitate ageing research in musculoskeletal tissues. Multivariate models based on DNA methylation, termed epigenetic clocks, have shown promise as markers of biological age. However, the accuracy of existing epigenetic clocks in musculoskeletal tissues are no more, a...

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Literature Corpus work
5e5f6fc6-c598-5a08-b254-0c99e762d294
DOI
10.1101/2023.05.04.539347
Open publication

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MskAge - An Epigenetic Biomarker of Musculoskeletal Age Derived from a Genetic Algorithm Islands ModelDOI 10.1101/2023.05.04.539347
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