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Article

Association of telomere length with risk of complications in adult spinal deformity surgery: a pilot study of 43 patients

2 Dec 2022

Abstract excerpt

OBJECTIVE: Risk stratification is a critical element of surgical planning. Early tools were fairly crude, while newer instruments incorporate disease-specific elements and markers of frailty. It is unknown if discrepancies between chronological and cellular age can guide surgical planning or treatment. Telomeres are DNA-protein complexes that serve an important role in protecting genomic DNA. Their shortening is...

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PMID: 36461827
DOI: 10.3171/2022.10.spine22605

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