Article
Understanding cellular senescence: pathways involved, therapeutics and longevity aiding
18 Oct 2023
Abstract excerpt
A normal somatic cell undergoes cycles of finite cellular divisions. The presence of surveillance checkpoints arrests cell division in response to stress inducers: oxidative stress from excess free radicals, oncogene-induced abnormalities, genotoxic stress, and telomere attrition. When facing such stress when undergoing these damages, there is a brief pause in the cell cycle to enable repair mechanisms. Also, the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
