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Article

Gene polymorphism and prediction of toxicity to platinum-based chemotherapy in patients with gynecologic cancer.

Clinical and translational science - 1 Dec 2023

Huang Xuan, Li Junmin, Pang Xiaoying, Zhu Jialei, Pan Jiaqian, Li Yueyan, Tang Jing

Abstract excerpt

The relationship between single nucleotide polymorphisms (SNPs) at various loci and adverse drug reactions (ADRs) in patients with gynecologic cancer receiving platinum-based chemotherapy (PPCT) remains unexplored. This research aimed to investigate the correlation between SNPs at several loci (e.g., GSTP1 rs1695, MTHFR rs1801133, XPC rs2228001, TP53 rs1042522, and ERCC1 rs3212986) and ADRs in patients with...

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PMID: 38013655
DOI: 10.1111/cts.13642
PMCID: PMC10719482

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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