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Predictive value of clinical toxicities of chemotherapy with fluoropyrimidines and oxaliplatin in colorectal cancer by DPYD and GSTP1 gene polymorphisms

2020-12-08

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<title>Abstract</title> <p><bold>Background: </bold>Fluoropyrimidines and platinum are still widely used for colorectal cancer (CRC) management. Several studies have reported that mutations of dihydropyrimidine dehydrogenase (<italic>DPYD</italic>) and glutathione S-transferase pi-1 (<italic>GSTP1</italic>) polymorphisms are related to Chemotherapy-related adverse events. In the present study, we purposed to asse...

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Literature Corpus work
f5e97f28-3d35-5273-9a09-47d936b7f4b1
DOI
10.21203/rs.3.rs-73108/v3
Open publication

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