Article
Relationship between clinical toxicities and ERCC1 rs3212986 and XRCC3 rs861539 polymorphisms in cervical cancer patients.
The International journal of biological markers - 1 Jan 2018
Soares Sílvia, Nogueira Augusto, Coelho Ana, Assis Joana, Pereira Deolinda, Bravo Isabel, Medeiros Rui
Abstract excerpt
BACKGROUND: Several studies have suggested that there are single nucleotide polymorphisms (SNPs) that can be considered potential biomarkers in the prognosis and therapeutic response of cancer patients. The present study investigated the association between ERCC1 rs3212986 and XRCC3 rs861539 polymorphisms and clinical toxicities induced by chemoradiotherapy (CRT) in cervical cancer. METHODS: This hospital-based...
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