Article
Interferon-stimulated gene 15 polymorphisms are associated with spontaneous preterm birth in Taiwanese women.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Dec 2023
Chang Tzu-Yang, Wang Liang-Kai, Kuo Yi-Hsiu, Chen Chia-Yu, Pai Tun-Wen, Chen Chie-Pein
Abstract excerpt
PROBLEM: Immune and inflammatory responses are known to be major causes of preterm birth (PTB). The maternal genetic background plays an important role in the development of PTB. Interferon-stimulated gene 15 (ISG15) is an interferon-induced protein which can modulate immune cell activation and function. We aim to study if polymorphisms in the ISG15 gene are associated with spontaneous PTB (sPTB) risk in...
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