Article
Role of single nucleotide polymorphisms of cytokine genes in spontaneous preterm delivery.
Human immunology - 1 Nov 2006
Speer Esther Monika, Gentile Deborah Ann, Zeevi Adriana, Pillage Gina, Huo Dezheng, Skoner David Peter
Abstract excerpt
Intra-amniotic infections are implicated in spontaneous preterm delivery (PTD). Certain genetic polymorphisms are associated with increased production of proinflammatory and/or decreased production of anti-inflammatory cytokines, thereby possibly promoting PTD. We determined the relationship between maternal and fetal cytokine gene polymorphisms with occurrence and severity of spontaneous PTD (PTD after...
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