Article
Associations of maternal PLA2G4C and PLA2G4D polymorphisms with the risk of spontaneous preterm birth in a Chinese population.
Molecular medicine reports - 1 Jun 2017
Liu Guang-Jian, He Jian-Rong, Kuang Ya-Shu, Fan Xue-Jiao, Li Wei-Dong, Lu Jin-Hua, Xia Xiao-Yan, Liu Xiao-Dan, Chen Nian-Nian, Mai Wei-Bi, Xia Hui-Min, Qiu Xiu
Abstract excerpt
Preterm birth is the leading cause of mortality and morbidity in infants. Its etiology is multifactorial with genes and immune homeostasis. The authors investigated whether prostaglandin (PG) synthesis related single nucleotide polymorphisms (SNPs) PLA2G4C rs1366442 and PLA2G4D rs4924618 were associated with the risk of spontaneous preterm birth (SPTB) in a Chinese population of 114 cases of SPTB and 250 controls...
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