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Article

Specific gyrA Gene Mutations Correlate with High Prevalence of Discordant Levofloxacin Resistance in Mycobacterium tuberculosis Isolates from Beijing, China.

The Journal of molecular diagnostics : JMD - 1 Sept 2020

Huo Fengmin, Ma Yifeng, Li Shanshan, Xue Yi, Shang Yuanyuan, Dong Lingling, Li Yunxu, Pang Yu

Abstract excerpt

Although rapid, highly sensitive molecular diagnostics tests are useful for diagnosing fluoroquinolone-resistant tuberculosis (TB), results of molecular testing versus conventional sequential phenotypic drug susceptibility testing (pDST) are frequently discordant. This article determined the discordance rate of levofloxacin (LFX) resistance results, obtained via MeltPro TB molecular testing, versus pDST of...

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PMID: 32619641
DOI: 10.1016/j.jmoldx.2020.06.010

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