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Article

New trends in glioma cancer therapy: Targeting Na+/H+ exchangers

27 Jun 2019

Abstract excerpt

Abstract Glioma is the oneof the most prevalent primarybrain tumors. There is a variety of oxidative stresses, inflammatory pathways, apoptosis signaling, and Na+/H + exchangers (NHEs) involved in the pathophysiology of glioma. Previous studies have indicated a relationship between NHEs and some molecular pathways in glioma. NHEs, including NHE1, NHE5, and NHE9 affect apoptosis, tumor‐associated macrophage...

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PMID: 31250444
DOI: 10.1002/jcp.29014

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