Article
Detection of Immune Escape and Basal Core Promoter/Precore Gene Mutations in Hepatitis B Virus Isolated from Asymptomatic Hospital Attendees in Two Southwestern States in Nigeria.
Viruses - 31 Oct 2023
Sobajo Oguntope Adeorike, Oguzie Judith Uche, Adegboyega Benjamin, Eromon Philomena, Happi Christian, Komolafe Isaac, Folarin Onikepe
Abstract excerpt
Several mutations in the surface (S), basal core promoter (BCP), and precore (PC) genes of the hepatitis B virus have been linked to inaccurate diagnosis and the development of immune escape mutants (IEMs) of the infection, which can lead to chronic infection. Understanding the prevalence and spread of these mutations is critical in the global effort to eliminate HBV. Blood samples were collected from 410 people...
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