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Genome-Wide Identification of Variants Associated with Antifungal Drug Resistance.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2023

Martinez-Zurita Aina, Cuomo Christina A

Abstract excerpt

Genomic approaches are widely applied to study the genetic basis of antifungal drug resistance in clinical isolates and experimental studies. Whole-genome sequencing of clinical isolates can comprehensively identify mutations associated with drug resistance and their frequency across fungal populations. In addition, genome comparison of serially collected isolates, such as from patient samples or in vitro drug...

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PMID: 37024697
DOI: 10.1007/978-1-0716-3155-3_7

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