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Article

Modifiable pathways for colorectal cancer: a mendelian randomisation analysis.

The lancet. Gastroenterology & hepatology - 1 Jan 2020

Cornish Alex J, Law Philip J, Timofeeva Maria, Palin Kimmo, Farrington Susan M, Palles Claire, Jenkins Mark A, Casey Graham, Brenner Hermann, Chang-Claude Jenny, Hoffmeister Michael, Kirac Iva, Maughan Tim, Brezina Stefanie, Gsur Andrea, Cheadle Jeremy P, Aaltonen Lauri A, Tomlinson Ian, Dunlop Malcolm G, Houlston Richard S

Abstract excerpt

BACKGROUND: Epidemiological studies have linked lifestyle, cardiometabolic, reproductive, developmental, and inflammatory factors to the risk of colorectal cancer. However, which specific factors affect risk and the strength of these effects are unknown. We aimed to examine the relationship between potentially modifiable risk factors and colorectal cancer. METHODS: We used a random-effects model to examine the...

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Identifiers

PMID: 31668584
DOI: 10.1016/S2468-1253(19)30294-8
PMCID: PMC7026696

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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