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Red and Processed Meat Intake, Polygenic Risk and the Prevalence of Colorectal Neoplasms: Results from a Screening Colonoscopy Population.

Nutrients - 8 Aug 2024

Fu Ruojin, Chen Xuechen, Seum Teresa, Hoffmeister Michael, Brenner Hermann

Abstract excerpt

High red and processed meat intake and genetic predisposition are risk factors of colorectal cancer (CRC). However, evidence of their independent and joint associations on the risk of colorectal neoplasms is limited. We assessed these associations among 4774 men and women undergoing screening colonoscopy. Polygenic risk scores (PRSs) were calculated based on 140 loci related to CRC. We used multiple logistic...

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PMID: 39203746
DOI: 10.3390/nu16162609
PMCID: PMC11357662

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