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Article

New insights into the immunopathogenesis of systemic lupus erythematosus.

Nature reviews. Rheumatology - 22 Nov 2016

Tsokos George C, Lo Mindy S, Costa Reis Patricia, Sullivan Kathleen E

Abstract excerpt

The aetiology of systemic lupus erythematosus (SLE) is multifactorial, and includes contributions from the environment, stochastic factors, and genetic susceptibility. Great gains have been made in understanding SLE through the use of genetic variant identification, mouse models, gene expression studies, and epigenetic analyses. Collectively, these studies support the concept that defective clearance of immune...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27872476
DOI: 10.1038/nrrheum.2016.186

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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