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Article

Transcriptome-wide association studies: recent advances in methods, applications and available databases.

Communications biology - 1 Sept 2023

Mai Jialin, Lu Mingming, Gao Qianwen, Zeng Jingyao, Xiao Jingfa

Abstract excerpt

Genome-wide association study has identified fruitful variants impacting heritable traits. Nevertheless, identifying critical genes underlying those significant variants has been a great task. Transcriptome-wide association study (TWAS) is an instrumental post-analysis to detect significant gene-trait associations focusing on modeling transcription-level regulations, which has made numerous progresses in recent...

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PMID: 37658226
DOI: 10.1038/s42003-023-05279-y
PMCID: PMC10474133

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