Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolution of the coronavirus spike protein in the full-length genome and defective viral genome under diverse selection pressures.

The Journal of general virology - 1 Nov 2023

Lin Ching-Hung, Tam Hon-Man-Herman, Yang Cheng-Yao, Hsieh Feng-Cheng, Wang Jiun-Long, Yang Chun-Chun, Hsu Hsuan-Wei, Liu Hao-Ping, Wu Hung-Yi

Abstract excerpt

How coronaviruses evolve by altering the structures of their full-length genome and defective viral genome (DVG) under dynamic selection pressures has not been studied. In this study, we aimed to experimentally identify the dynamic evolutionary patterns of the S protein sequence in the full-length genome and DVG under diverse selection pressures, including persistence, innate immunity and antiviral drugs. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coronavirus
Share to Coronavirus Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Viral

Share to Mutation

Share to Spike Glycoprotein, Coronavirus

Source

Open in PubMed Open full text

Identifiers

PMID: 37997889
DOI: 10.1099/jgv.0.001920
PMCID: PMC10768696

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolution of the coronavirus spike protein in the full-length genome and defective viral genome under diverse selection pressures.PMID 37997889Read ↗

Molecular Evolution of SARS-CoV-2 Structural Genes: Evidence of Positive Selection in the Spike GlycoproteinSemantic proximity Read ↗

Naturally occurring SARS-CoV-2 gene deletions close to the spike S1/S2 cleavage site in the viral quasispecies of COVID19 patientsSemantic proximity Read ↗

Adaptive evolution of the spike gene of SARS coronavirus: changes in positively selected sites in different epidemic groupsSemantic proximity Read ↗

Detecting Potentially Adaptive Mutations from the Parallel and Fixed Patterns in SARS-CoV-2 Evolution.Semantic proximity Read ↗

Mutation analysis of 20 SARS virus genome sequences: evidence for negative selection in replicase ORF1b and spike gene.Semantic proximity Read ↗

RNA structure-altering mutations underlying positive selection on Spike protein reveal novel putative signatures to trace crossing host-species barriers in Betacoronavirus.Semantic proximity Read ↗

Genetic drift of human coronavirus OC43 spike gene during adaptive evolution.Semantic proximity Read ↗

Convergent Evolution and Host-Limiting Impacts of SARS-CoV-2 Revealed by Cellular Experiments.Semantic proximity Read ↗

Adaptive Evolution of the Spike Protein in CoronavirusesSemantic proximity Read ↗

Naturally occurring SARS-CoV-2 gene deletions close to the spike S1/S2 cleavage site in the viral quasispecies of COVID19 patientsSemantic proximity Read ↗

An evolutionary theory on virus mutation in COVID-19.Semantic proximity Read ↗

Genomics, proteomics and evolution of dengue virusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.