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Article

Mutation analysis of 20 SARS virus genome sequences: evidence for negative selection in replicase ORF1b and spike gene.

Acta pharmacologica Sinica - 1 Aug 2003

Hu Lan-Dian, Zheng Guang-Yong, Jiang Hai-Song, Xia Yu, Zhang Yi, Kong Xiang-Yin

Abstract excerpt

AIM: Recently, more SARS-CoV virus genome sequences are released to the GenBank database. The aim of this study is to reveal the evolution forces of SARS-CoV virus by analyzing the nucleotide mutations in these sequences. METHODS: We obtained 20 SARS-CoV virus genome sequences from NCBI database,...

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PMID: 12904271

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12904271-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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