Article
CCR5 promoter region polymorphisms in systemic lupus erythematosus.
International journal of immunogenetics - 1 Feb 2024
Schauren Juliana da Silveira, de Oliveira Amanda Henrique, Consiglio Camila Rosat, Monticielo Odirlei André, Xavier Ricardo Machado, Nunes Natália Schneider, Ellwanger Joel Henrique, Chies José Artur Bogo
Abstract excerpt
This study investigated the impacts of CCR5 promoter region polymorphisms on the development of systemic lupus erythematosus (SLE) by comparing CCR5 genotypes and haplotypes from SLE patients with ethnically matched controls. A total of 382 SLE patients (289 European-derived and 93 African-derived) and 375 controls (243 European-derived and 132 African-derived) were genotyped for the CCR2-64I G > A (rs1799864),...
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