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Article

Expression quantitative trait loci analysis in rheumatoid arthritis identifies tissue specific variants associated with severity and outcome.

Annals of the rheumatic diseases - 15 Feb 2024

Goldmann Katriona, Spiliopoulou Athina, Iakovliev Andrii, Plant Darren, Nair Nisha, Cubuk Cankut, McKeigue Paul, Barnes Michael R, Barton Anne, Pitzalis Costantino, Lewis Myles J

Abstract excerpt

OBJECTIVE: Genome-wide association studies have successfully identified more than 100 loci associated with susceptibility to rheumatoid arthritis (RA). However, our understanding of the functional effects of genetic variants in causing RA and their effects on disease severity and response to treatment remains limited. METHODS: In this study, we conducted expression quantitative trait locus (eQTL) analysis to...

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Share to Arthritis, Rheumatoid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 37979960
DOI: 10.1136/ard-2023-224540
PMCID: PMC10894812

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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