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Cervix cytology samples revealed increased methylation of the human markers FAM19A4 / miR124‐2 up to 8 years before adenocarcinoma

14 Nov 2023

Abstract excerpt

INTRODUCTION: Methylation analysis of the promoter region of tumor-suppressor genes has previously shown high sensitivity for detection of high-grade cervical intraepithelial neoplasia (CIN) and cancer. HPV-testing has a high sensitivity to identify women at risk to develop cancer, and has been implemented in cervical screening programs in several countries. But in most HPV-positive women the infection will clear...

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PMID: 37964497
DOI: 10.1111/aogs.14707

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