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Article

Cervical cancer risk in HPV-positive women after a negative FAM19A4/mir124-2 methylation test: A post hoc analysis in the POBASCAM trial with 14 year follow-up.

International journal of cancer - 15 Sept 2018

De Strooper Lise M A, Berkhof Johannes, Steenbergen Renske D M, Lissenberg-Witte Birgit I, Snijders Peter J F, Meijer Chris J L M, Heideman Daniëlle A M

Abstract excerpt

DNA methylation analysis of cervical scrapes using FAM19A4 and mir124-2 genes has shown a good clinical performance in detecting cervical cancer and advanced CIN lesions in need of treatment in HPV-positive women. To date, longitudinal data on the cancer risk of methylation test-negative women are lacking. In our study, we assessed the longitudinal outcome of FAM19A4/mir124-2 methylation analysis in an...

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Identifiers

PMID: 29663363
DOI: 10.1002/ijc.31539
PMCID: PMC6099282

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Cervical cancer risk in HPV-positive women after a negative FAM19A4/mir124-2 methylation test: A post hoc analysis in the POBASCAM trial with 14 year follow-up.PMID 29663363Read ↗

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