Article
FAM19A4/miR124-2 Methylation Testing and Human Papillomavirus (HPV) 16/18 Genotyping in HPV-Positive Women Under the Age of 30 Years.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 8 Feb 2023
Vink Frederique J, Meijer Chris J L M, Hesselink Albertus T, Floore Arno N, Lissenberg-Witte Birgit I, Bonde Jesper H, Pedersen Helle, Cuschieri Kate, Bhatia Ramya, Poljak Mario, Oštrbenk Valenčak Anja, Hillemanns Peter, Quint Wim G V, Del Pino Marta, Kenter Gemma G, Steenbergen Renske D M, Heideman Daniëlle A M, Bleeker Maaike C G
Abstract excerpt
BACKGROUND: High-grade squamous intraepithelial lesions (HSIL) or cervical intraepithelial neoplasia (CIN) grade 2/3 lesions in human papillomavirus (HPV)-positive women <30 years of age have high spontaneous regression rates. To reduce overtreatment, biomarkers are needed to delineate advanced CIN lesions that require treatment. We analyzed the FAM19A4/miR124-2 methylation test and HPV16/18 genotyping in...
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