Article
Reliable identification of women with CIN3+ using hrHPV genotyping and methylation markers in a cytology-screened referral population.
International journal of cancer - 1 Jan 2019
Leeman Annemiek, Del Pino Marta, Marimon Lorena, Torné Aureli, Ordi Jaume, Ter Harmsel Bram, Meijer Chris J L M, Jenkins David, Van Kemenade Folkert J, Quint Wim G V
Abstract excerpt
Cervical screening aims to identify women with high-grade squamous intraepithelial lesion/cervical intraepithelial neoplasia 2-3 (HSIL/CIN2-3) or invasive cervical cancer (ICC). Identification of women with severe premalignant lesions or ICC (CIN3+) could ensure their rapid treatment and prevent overtreatment. We investigated high-risk human papillomavirus (hrHPV) detection with genotyping and methylation of...
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