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Article

Hofbauer cell function in the term placenta associates with adult cardiovascular and depressive outcomes

14 Nov 2023

Abstract excerpt

Pathological placental inflammation increases the risk for several adult disorders, but these mediators are also expressed under homeostatic conditions, where their contribution to adult health outcomes is unknown. Here we define an inflammation-related expression signature, primarily expressed in Hofbauer cells of the term placenta and use expression quantitative trait loci to create a polygenic score (PGS)...

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PMID: 37963865
DOI: 10.1038/s41467-023-42300-8

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