Article

Homeostatic inflammation in the placenta is protective against adult cardiovascular and depressive outcomes

2023-02-21

Abstract excerpt

Pathological placental inflammation increases the risk for several adult disorders, but these mediators are also expressed under homeostatic conditions, where their contribution to adult health outcomes is unknown. Here we define an expression signature of homeostatic inflammation in the term placenta and use expression quantitative trait loci (eQTLs) to create a polygenic score (PGS) predictive of its expression....

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Literature Corpus work: f51531c0-8745-59b8-8a52-523c2e40b676
DOI: 10.1101/2023.02.20.23286171

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