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A novel lactate metabolism-related signature predicts prognosis and tumor immune microenvironment of breast cancer

7 Sept 2022

Abstract excerpt

Background: Lactate, an intermediate product of glycolysis, has become an essential regulator of tumor maintenance, development, and metastasis. Lactate can drive tumors by changing the microenvironment of tumor cells. Because of lactate’s important role in cancer, we aim to find a novel prognostic signature based on lactate metabolism-related genes (LMRGs) of breast cancer (BC). Methods: RNA-sequencing data and...

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PMID: 36171887
DOI: 10.3389/fgene.2022.934830

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