Back to search

Article

A novel lactylation-related signature predicts the prognosis and is associated with immune infiltration in thyroid cancer

2025-03-20

Abstract excerpt

<title>Abstract</title> <p><bold>Background​: </bold>Epigenetic regulator lactate, a glycolysis product, affects gene expression via histone lactylation, promoting tumor growth and immunosuppression. But its related genes' role in thyroid carcinoma (THCA) remains unclear.​ <bold>Methods​: </bold>Lactylation - related genes from TCGA were consensus clustered. DEGs between clusters were analyzed via Cox regression,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
38ddefa8-ed9c-5d5e-acaa-253deca0879d
DOI
10.21203/rs.3.rs-6253601/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A novel lactylation-related signature predicts the prognosis and is associated with immune infiltration in thyroid cancerDOI 10.21203/rs.3.rs-6253601/v1
Identification of lactylation related model to predict prognostic, tumor infiltrating immunocytes and response of immunotherapy in gastric cancerSemantic proximity
Machine learning-based prognostic model of lactylation-related genes for predicting prognosis and immune infiltration in patients with lung adenocarcinomaSemantic proximity
Characterization of Lactate Metabolism Score in Breast and Thyroid Cancers to Assist Immunotherapy via Large-Scale Transcriptomic Data AnalysisSemantic proximity
A Lactate-related LncRNA Model for Predicting Prognosis, Immune Landscape and Therapeutic Response in Breast CancerSemantic proximity
Lactylation-related gene signature accurately predicts prognosis and immunotherapy response in gastric cancerSemantic proximity
The role of lactate metabolism-related LncRNAs in the prognosis, mutation, and tumor microenvironment of papillary thyroid cancer.Semantic proximity
Identification of lactylation-related subgroups and prognosis model in hepatocellular carcinomaSemantic proximity
M6A and lactylation modification-related signature predicts prognosis and immunotherapy response in hepatocellular carcinomaSemantic proximity
Lactylation drives tumor microenvironment remodeling and immune evasion in esophageal cancer revealed by multiomics and single cell transcriptomicsSemantic proximity
Multi-omics analysis identifies lactylation-mediated immune biomarkers in esophageal cancerSemantic proximity
Novel lactylation-related signature to predict prognosis for pancreatic adenocarcinomaSemantic proximity
Identification of a lactylation-related gene signature to characterize subtypes of hepatocellular carcinoma using bulk sequencing dataSemantic proximity
Select a neighboring publication to make it the new centre.